Cirrhosis in children and adolescents: An overview

Table 1 Diseases potentially resulting in cirrhosis in children and adolescents

Biliary obstruction

Biliary atresia

Choledochal cysts

Gallstones

Bile duct stenosis

Familial intrahepatic cholestasis

Alagille syndrome

FIC1 deficiency (ATP8B1)

BSEP deficiency (ABCB11)

MDR3 deficiency (ABCB4)

Defects of bile acid synthesis

Hepatotropic viral infections

Hepatitis B and D

Hepatitis C

Hepatitis E

Inherited genetic-metabolic diseases

α-1-antitrypsin deficiency

Glycogenosis type III and IV

Galactosemia

Fructosemia

Tyrosinemia type 1

Wilson’s disease

Mitochondrial hepatopathies

Late cutaneous porphyria

Cystic fibrosis

Hemochromatosis

Wolman disease

Drugs and toxins

Total parenteral nutrition

Isoniazid

Methotrexate

Vitamin A intoxication

Autoimmune diseases

Autoimmune hepatitis

Primary sclerosing cholangitis

Vascular alterations

Budd-Chiari syndrome

Veno-occlusive disease

Congenital cardiopathy

Congestive heart failure

Constrictive pericarditis

Other: Fatty liver disease, Neonatal hepatitis, Zellweger disease