Copyright
©The Author(s) 2015.
World J Hepatol. Mar 27, 2015; 7(3): 327-343
Published online Mar 27, 2015. doi: 10.4254/wjh.v7.i3.327
Published online Mar 27, 2015. doi: 10.4254/wjh.v7.i3.327
Table 2 Clinico-epidemiological and laboratory features of mixed cryoglobulinemia1
Epidemiological features | |
Mean age at disease onset ± SD, yr (range) | 55 ± 12 (29-72) |
Mean disease duration ± SD, yr (range) | 12 ± 10 (1-40) |
Female/male ratio | 3 |
Clinical features | |
Purpura | 98 |
Weakness | 98 |
Arthralgias | 91 |
Arthritis (non-erosive) | 8 |
Raynaud’s phenomenon | 32 |
Sicca syndrome | 51 |
Peripheral neuropathy | 81 |
Renal involvement2 | 31 |
Liver involvement | 73 |
B cell non-Hodgkin’s lymphoma | 11 |
Hepatocellular carcinoma | 3 |
Serological and virological features | |
Mean cryocrit (SD) | 4.4% (12) |
Type II/type III mixed cryoglobulins | 2/1 |
Mean C3 (SD) (nv 60-130 mg/dL) | 93 (30) |
Mean C4 (SD) (nv 20-55 mg/dL) | 10 (12) |
Anti-nuclear antibodies | 30 |
Anti-mitochondrial antibodies | 9 |
Anti-smooth muscle antibodies | 18 |
Anti-extractable nuclear antigen antibodies | 8 |
Anti-HCV antibodies ± HCV RNA | 92 |
Anti-HBV antibodies | 32 |
HBsAg | 1 |
- Citation: Ferri C, Sebastiani M, Giuggioli D, Colaci M, Fallahi P, Piluso A, Antonelli A, Zignego AL. Hepatitis C virus syndrome: A constellation of organ- and non-organ specific autoimmune disorders, B-cell non-Hodgkin’s lymphoma, and cancer. World J Hepatol 2015; 7(3): 327-343
- URL: https://www.wjgnet.com/1948-5182/full/v7/i3/327.htm
- DOI: https://dx.doi.org/10.4254/wjh.v7.i3.327