Prediction of liver cirrhosis, using diagnostic imaging tools

Table 2 Diagnostic performance of magnetic resonance elastography for hepatic fibrosis

Ref.	Year	Study method	Imaging instrument	Etiologies	No. of patients	Sensitivity (%)	Specificity (%)	Cut-offs	AUROC	Fibrosis score
Singh et al[66]	2015	Meta-analysis	1.5 Tesla, variable	Chronic viral and nonviralhepatopathies	697	79	81	3.66 kPa	0.88	≥ F2
Venkatesh et al[67]	2015	Retrospective	1.5 Tesla, (GE, Signa)	Chronic viral and nonviralhepatopathies	62	100	96.5	3.37 kPa	0.99	≥ F2
Yoon et al[56]	2014	Prospective	1.5 Tesla (GE, SignaHDx)	Chronic viral and nonviralhepatopathies	94	78.8	75.6	6.65 kPa	0.852	≥ F2
Venkatesh et al[68]	2014	Prospective	1.5 Tesla (GE, Signa)	HBV	63	97.4	100	3.2 kPa	0.99	≥ F2
Shi et al[69]	2014	Prospective	3.0 Tesla (GE, Signa Excite HD)	HBV	113	95	94.5	4.07 kPa	0.986	≥ F2
Loomba et al[70]	2014	Prospective	3.0 Tesla (GE, Signa Excite HD)	Nonalcoholic fatty liver disease	117	86	91	3.63 kPa	0.924	≥ F3
Bohte et al[71]	2014	Prospective	3.0 Tesla (Philips, Intera)	HBV, HCV	103	62	96	2.18 kPa	0.928	≥ F2
Kim et al[72]	2013	Retrospective	1.5 Tesla (GE, Signa)	Nonalcoholic fatty liver disease	142	85	92.9	4.15 kPa	0.954	≥ F3
Wang et al[73]	2012	Meta-analysis	1.5 Tesla, variable	Chronic viral and nonviralhepatopathies	972	94	95	N/A	0.98	≥ F2
Rustogi et al[54]	2012	Retrospective	1.5 Tesla (Siemens, Magnetom)	Chronic viral and nonviralhepatopathies	72	85.4	88.4	5.9 kPa	N/A	≥ F3
Kim et al[74]	2011	Prospective	1.5 Tesla GE, SignaHDx)	Chronic viral and nonviralhepatopathies	55	89.7	87.1	3.05 kPa	N/A	≥ F2

AUROC: Area under receiver operating characteristic; HBV: Hepatitis B virus; HCV: Hepatitis C virus; N/A: Not applicable.