Hepatitis C cirrhosis: New perspectives for diagnosis and treatment

doi:10.4254/wjh.v7.i14.1843

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jul 18, 2015; 7(14): 1843-1855
Published online Jul 18, 2015. doi: 10.4254/wjh.v7.i14.1843

Table 6 Sustained virologic response achieved in the COSMOS study[43]

Cohort	Regimen	Duration (wk)	SVR12
Cohort 1: Prior non-responder HCV	SMV/SOF + RBV	24	79%
patients with METAVIR scores (F0-F2)	SMV/SOF	24	93%
	SMV/SOF + RBV	12	96%
	SMV/SOF	12	93%
Cohort 2: Prior non-responder and	SMV/SOF + RBV	24	93%
treatment naïve HCV patients with	SMV/SOF	24	100%
METAVIR scores (F3-F4)	SMV/SOF + RBV	12	93%
	SMV/SOF	12	93%

SOF: Sofosbuvir; SMV: Simeprevir; RBV: Ribavirin; SVR12: Sustained virologic response at 12 wk; HCV: Hepatitis C virus.

Citation: Khullar V, Firpi RJ. Hepatitis C cirrhosis: New perspectives for diagnosis and treatment. World J Hepatol 2015; 7(14): 1843-1855
URL: https://www.wjgnet.com/1948-5182/full/v7/i14/1843.htm
DOI: https://dx.doi.org/10.4254/wjh.v7.i14.1843