Hepatitis C cirrhosis: New perspectives for diagnosis and treatment

Table 2 Various scoring system for the histological staging for liver fibrosis

Stage	IASL score	Bats-Ludwig score	Metavir	Ishak score
0	No fibrosis	No fibrosis	No fibrosis	No fibrosis
1	Mild fibrosis	Fibrous portal expansion	Presence of periportal fibrotic expansion	Fibrous expansion of some portal areas with or without short fibrous septae
2	Moderate fibrosis	Rare bridges or septae	Periportal septae 1 (septum)	Fibrous expansion of most portal areas with or without short fibrous septae
3	Severe fibrosis	Numerous bridges or septae	Porto-central septae	Fibrous expansion of most portal areas with occasional portal to portal bridging
4	Cirrhosis	Cirrhosis	Cirrhosis	Fibrous expansion of most portal areas with marked bridging (portal to portal and portal to central)
5				Marked bridging (portal to portal and portal to central) with occasional nodules (incomplete cirrhosis)
6				Cirrhosis

Adapted from Ghany et al[21].