Efficacy of tolvaptan in patients with refractory ascites in a clinical setting

Figure 4 Receiver operating characteristic analysis. A: A reduction in urine osmolality > 25% was the single best cut-off level for improvement of refractory ascites with 89.5% sensitivity and 59.1% specificity; B: A combination of urine output > 1800 mL within the first 24 h and a 30% reduction in urine osmolality were the best cut-off levels for improvement of refractory ascites with 84.2% sensitivity and 81.8% specificity.