1H nuclear magnetic resonance spectroscopy-based metabonomic study in patients with cirrhosis and hepatic encephalopathy

Table 5 Results for amines, glycerol and myo-inositol are shown

	Chemical shift	Cirrhotics	Encephalopathics	Controls
Methylamine	2.54	0.17 ± 0.03	0.19 ± 0.03	0
Dimethylamine	2.72	0.29 ± 0.03	0.31 ± 0.04	0
Tmao	3.27	0.45 ± 0.07	0.51 ± 0.08	0
Glycerol	3.79	0.53 ± 0.09b	0.2 ± 0.02b	0.08 ± 0.02
Myoinositol	3.63	0.37 ± 0.06a	0.19 ± 0.04	0.16 ± 0.03

Methylamine, dimethylamine and TMAO were present in patients and absent in controls. Glycerol concentrations were significantly higher in patients than controls (^bP < 0.01). Myo-inositol concentrations were significantly higher in cirrhotics (^aP < 0.015) but there were no differences between encephalopathics and controls.