Guide for diagnosis and treatment of hepatocellular carcinoma

doi:10.4254/wjh.v7.i12.1632

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jun 28, 2015; 7(12): 1632-1651
Published online Jun 28, 2015. doi: 10.4254/wjh.v7.i12.1632

Table 4 Ongoing randomised phase II-III trials aimed at changing the standard of care in hepatocellular carcinoma management during the period 2012-2013[10]

Indication	Randomised studies
Adjuvant	Sorafenib vs placebo
Intermediate HCC	Chemoembolisation ± sorafenib
	Chemoembolisation ± brivanib
	Chemoembolisation ± everolimus
Advanced HCC
First line	Sorafenib ± erlotinib
	Sorafenib vs brivanib
	Sorafenib vs sunitinib
	Sorafenib vs linifanib
	Sorafenib ± yttrium-90
	Sorafenib ± doxorubicin
Second line	Brivanib vs placebo
	Everolimus vs placebo
	Ramucirmab vs placebo

HCC: Hepatocellular carcinoma.

Citation: Attwa MH, El-Etreby SA. Guide for diagnosis and treatment of hepatocellular carcinoma. World J Hepatol 2015; 7(12): 1632-1651
URL: https://www.wjgnet.com/1948-5182/full/v7/i12/1632.htm
DOI: https://dx.doi.org/10.4254/wjh.v7.i12.1632