Treatment of chronic hepatitis C in liver transplant candidates and recipients: Where do we stand?

Table 4 Major studies of interferon-free regimens for treatment of hepatitis C virus positive liver transplant candidates reported in 2014

Ref.	n	CP score	Antiviral scheme	Virological response
Curry et al[37]	61	≤ 7	SOF + RBV for 48 wk or until LT	69% (12 wk after LT)
Gane et al[39]	20	7-9	SOF ± RBV + ledipasvir for 12 wk	89% (SVR 4 wk)
Flamm et al[40]	108	Decompensated cirrhosis (range: 7-12)	SOF + RBV + ledipasvir for 12 or 24 wk	87% and 89%, respectively (SVR 12 wk)
Afdhal et al[38]	50	5-10	SOF + RBV for 48 wk	100% CP class A
				93% CP class B at 24 wk under treatment

n: Number of patients; CP: Child-Pugh; SOF: Sofosbuvir; RBV: Ribavirin; SVR: Sustained virological response.