Review
Copyright ©The Author(s) 2015.
World J Hepatol. Jun 28, 2015; 7(12): 1606-1616
Published online Jun 28, 2015. doi: 10.4254/wjh.v7.i12.1606
Table 1 Direct acting antivirals commenced on patients with decompensated cirrhosis or recipients after liver transplantation
Approved protease inhibitors
BoceprevirNS3-4A serine protease inhibitors
TelaprevirSecond-wave NS3/4A protease inhibitor
Simeprevir
Approved NS5A inhibitors
DaclatasvirNS5A inhibitor
Approved NS5B RNA-dependent RNA polymerase nucleotide inhibitor
SofosbuvirNS5B RNA-dependent RNA polymerase nucleotide inhibitor
Newer DAAs evaluated in combination regimens without Peg-IFN
Ledipasvir (formerly GS-5885)NS5A inhibitor
ABT-450NS3/4A protease inhibitor
Ombitasvir (formerly ABT-267)NS5A inhibitor
Dasabuvir (formerly ABT-333)Non-nucleoside NS5B polymerase inhibitor