Burden of nonalcoholic fatty liver disease and advanced fibrosis in a Texas Hispanic community cohort

Table 1 Formulae and cut-off scores of diagnostic panels for detection of liver fibrosis

Diagnostic panel	Formula	Cut-off scores for advanced fibrosis
		Absent	Present
BARD score[8]	Scale 0-4		≥ 2
	BMI ≥ 28 kg/m2 = 1 point
	AST/ALT ratio ≥ 0.8 = 2 points
	DM = 1 point
FIB4 index[9]	Age (yr) × AST (U/L)]/(platelet (109) × [ALT (U/L)]1/2	< 1.3	> 2.67
APRI[10]	(AST/ULN)/platelets (109/L) × 100	≤ 0.5	> 1.5
NAFLD fibrosis score[15]	-1.675 + 0.037 × age (yr) + 0.094 × BMI	< -1.455	> 0.676
	(kg/m2) + 1.13 × IFG/DM (yes = 1, no = 0)
	+ 0.99 × AST/ALT ratio - 0.013 × platelet
	(× 109/L) - 0.66 × albumin (g/dL)

BMI: Body mass index; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; ULN: Upper limit of normal; DM: Diabetes mellitus; IFG: Impaired fasting glucose; NAFLD: Nonalcoholic fatty liver disease.