MicroRNAs dysregulation in hepatocellular carcinoma: Insights in genomic medicine

Table 1 Upregulated miRNAs in hepatocellular carcinoma

MiRNA	Cellular process	Ref.
MiR-10a	Epithelial to mesenchymal transition and metastasis	[50]
MiR-130a	Drug resistance	[51]
MiR-135a	Metastasis	[52]
MiR-143	Metastasis	[53]
MiR-155	Proliferation and tumorigenesis	[54]
MiR-18a	Proliferation	[55]
MiR-181b	Cell growth, tumorigenesis and metastasis	[56]
MiR-182	Metastasis	[57]
MiR-183	Apoptosis	[47]
MiR-21	Metastasis and drug resistance	[39,58,59]
MiR-210	Metastasis, apoptosis and proliferation	[60,61]
MiR-216a	Tumorigenesis	[62]
MiR-221	Apoptosis, proliferation and angiogenesis	[42,45,63,64]
MiR-224	Metastasis, proliferation and apoptosis	[65-67]
MiR-23a	Gluconeogenesis	[68]
MiR-373	Cell cycle	[69]
MiR-301a	Metastasis	[70]
MiR-490-3p	Epithelial to mesenchymal transition	[71]
MiR-519d	Proliferation, invasion and apoptosis	[72]
MiR-550a	Metastasis	[73]
MiR-590-5p	Metastasis and proliferation	[74]
MiR-615-5p	Cell growth and migration	[75]
MiR-657	Proliferation	[76]
MiR-96	Proliferation	[77,78]
MiR-222	Metastasis	[79]

MiRNAs: MicroRNAs.