Genetic ancestry analysis in non-alcoholic fatty liver disease patients from Brazil and Portugal

Table 1 Baseline characteristics of Brazilian and Portuguese study population according to non-alcoholic fatty liver disease status n (%)

	Brazil (n = 131)			Portugal (n = 90)
	NASH	S. Steatosis	P-value	NASH	S. Steatosis	P-value
	86 (65.6)	45 (34.4)		24 (26.7)	66 (73.3)
Gender
Female	61 (70.1)	26 (29.9)	0.2	20 (28.6)	50 (71.4)	0.6
Male	25 (56.8)	19 (43.2)		4 (20.0)	16 (80.0)
Age (yr)	56 ± 1.1	51 ± 1.5	20.006	47 ± 12.4	47 ± 10.2	0.3
Diabetes-2	71 (82.4)	8 (17.6)	23.7 × 10-9	14 (33.3)	28 (66.7)	0.2
Fasting glucose (mg/dL)	124.9 ± 5.2	106.0 ± 5.3	20.001	97.3 ± 28.2	92.6 ± 18.4	0.3
HOMA ≥ 2.5 - mean	5.3	4.6	20.04	4.9	4.8	0.5
HOMA ≥ 2.5 - n	75 (70.8)	31 (29.2)	20.02	15 (45.5)	18 (54.5)	0.5
Hypertension	59 (68.2)	14 (31.8)	28.0 × 10-5	12 (20.1)	34 (73.9)	20.003
ALT (IU/L)	38.3 ± 0.6	33 ± 5.2	0.2	31.7 ± 30.6	30.56 ± 15.9	0.7
AST (IU/L)	22 ± 22.5	32.8 ± 3.2	20.009	25.9 ± 24.8	25.06 ± 11.2	0.7
1Dyslipidemia	54 (63.0)	17 (37.0)	20.009	24 (100)	55 (83)	20.03

¹High levels of cholesterol and/or triglyceride;

²Statistically significant results, P < 0.05. NASH: Nonalcoholic steatohepatitis; S. Steatosis: Simple steatosis; HOMA: Homeostatic Model of Assessment; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase.