Management of hepatocellular carcinoma: Predictive value of immunohistochemical markers for postoperative survival

Table 3 Clinicopathological parameters affecting the association between p53 expression and prognosis in this review (n)

Ref.	Number of	Positive rate (%)	HBsAg/HCVAb	Edmondson grade		TNM stage		Tumor size
	patients		positive	I + II	III + IV (1)	I + II	III + IV	≤5 cm	> 5 cm
				Well/moderate/poor (2)
Tseng et al[11]	113	37.1	79/34	84	29 (1)	54	59	Not reported
Hu et al[13]	124	41.9	83/30	20/38/13 (2)		61	63	Not reported
Kang et al[14]	83	96.4	59/8	27	56 (1)	Not reported		57	26
Stroescu et al[16]	47	68	40/0	19	28 (1)	Not reported		20	27
Sung et al[17]	105	19	82/6	78	27 (1)	Not reported		> 3 cm	52
Qin et al[19]	113	22	40/25	55	58 (1)	Not reported		48	55
Guo et al[20]	104	34.6	14/55	18/56/31 (2)		67	37	Not reported
Umemura et al[21]	90	33.3	Not reported	65	25 (1)	Not reported		37	53

TNM: Tumor-node-metastasis; HBsAg: Hepatitis B surface antigen; HCVAb: Hepatitis C virus antibody.