Pictures of focal nodular hyperplasia and hepatocellular adenomas

Figure 14 β-catenin activated, inflammatory hepatocellular adenoma. A, B: Woman born in 1967. Oral contraceptives 20 years, BMI 20.0 kg/m². By chance, discovery of one nodule 18 cm. Imaging hepatocellular adenoma (HCA). Segmentectomy IV and V 2005. A: HE: features of inflammatory HCA (IHCA): sinusoidal dilatation, thick vessels, mild inflammation. B: Glutamine synthase immunostaining is abnormal, but faint and heterogeneous with reinforcement around veins. C, D: Woman born in 1974; oral contraceptives 13 years. BMI 21.0 kg/m². By chance, discovery of one nodule 6.5 cm. Imaging IHCA. Segmentectomy VI and VII 2009. C: Marked but not diffuse CD34 immunostaining. D: Very few tumoral hepatocytes expressed aberrant nuclear β-catenin.