Circulating microRNAs in patients with non-alcoholic fatty liver disease

Table 1 Clinical and demographic characteristics of non-alcoholic fatty liver disease patients and controls

Variable	NAFLD (n = 20)	Control (n = 20)	P
Age (yr)	42.75 ± 8.17	44.50 ± 9.31	0.761
Sex (male/female)	9 (45.0)/11(55.0)	9 (45.0)/11 (55.0)	0.761
BMI (kg/m2)	31.86 ± 4.76	27.26 ± 3.07	0.006
Waist circumference (cm)	103.25 ± 13.65	90.75 ± 11.02	0.014
Systolic blood pressure (mmHg)	120.25 ± 8.66	120.25 ± 7.69	0.999
Diastolic blood pressure (mmHg)	76.50 ± 6.09	77.50 ± 8.96	0.761
Fasting glucose (mg/dL)	97.85 ± 13.88	86.80 ± 11.92	0.034
Triglycerides (mg/dL)	151.10 ± 65.06	167.70 ± 51.46	0.645
HDL-C (mg/dL)	43.00 (36.50-48.50)	45.00 (38.45-49.95)	0.761
LDL-C (mg/dL)	125.50 (100.00-139.00)	108.00 (89.25-121.25)	0.511
Insulin (mIU/mL)	14.81 (11.88-22.75)	11.76 (8.61-15.70)	0.229
HOMA-IR	4.05 (2.71-5.51)	2.21 (1.77-3.12)	0.034
Total biluribin (mg/dL)	0.65 (0.50-0.80)	0.60 (0.55-0.80)	0.761
Direct biluribin (mg/dL)	0.20 (0.12-0.25)	0.20 (0.10-0.20)	0.761
AST (IU/L)	45.00 (34.50-59.00)	21.00 (18.00-27.00)	< 0.001
ALT (IU/L)	68.50 (52.50-85.50)	18.50 (14.00-29.00)	< 0.001
AP (IU/L)	76.00 (55.50-96.00)	69.00 (57.00-78.50)	0.761
GGT (IU/L)	48.00 (33.00-73.00)	20.00 (14.50-33.00)	< 0.001
Creatinine (mg/dL)	0.87 ± 0.15	0.80 ± 0.18	0.401
WBC (μL)	6709.50 ± 1709.47	6618.00 ± 1425.37	0.892
Trombocyte (103/μL)	252.10 ± 64.85	275.90 ± 69.82	0.511
Hct	43.37 ± 3.53	44.25 ± 4.19	0.761

Values are expressed as n (%), mean ± SD or median (25^th-75^th percentiles). P values were adjusted with FDR to control multiple testing problem. NAFLD: Non-alcoholic fatty liver disease; BMI: Body mass index; HDL-C: High density lipoprotein cholesterol; LDL-C: Low density lipoprotein cholesterol; HOMA-IR: Homeostasis model assessment insulin resistance index; AST: Aspartate aminotransferase ; ALT: Alanine aminotransferase; AP: Alkaline phosphatase; GGT: Gamma glutamyl transferase; WBC: White blood cell.