Hepatitis E virus in patients with acute severe liver injury

Table 3 Hepatitis E virus immunoglobulin M positive patients

Patient ID	Gender	Age	Liver function tests (normal range)						HEV				Travel history	Initial/	Outcome
			ALT	Billirubin	ALP	Gamma GTP	Albumin	PT	IgG	IgM	RNA	Genotype		retrospective
			(10-50 IU/mL)	(< 17 μmol/L)	(40-125 IU/L)	(5-35 IU/mL)	(30-50 g/L)	(8-12 s)	(IU/mL)		(IU/mL)			diagnosis
1	Female	58	3648	92	540	480	35	16	48.4	+	6.4 × 104	3	Spain, Cornwall	DILI/hepatitis E	Survived
2	Female	67	98	516	256	Icteric1	19	14	36.49	+	1.4 × 103	3	Spain	Alcohol, T2Diabetes, obesity, CLD/hepatitis E	Died
3	Male	27	5288	140	186	368	27	35	24.7	+	-	-	London	POD/hepatitis E	Survived
4	Male	27	4044	269	253	Icteric1	38	25	42.05	+	1.9 × 104	1	India	Hepatitis E	Survived

¹GTP could not be calculated due to high serum bilirubin levels. Values obtained from serum samples taken on admission to SLTU. ALT: Alanine aminotransferase; ALP: Alkaline phosphatase; GTP: Glutamyl transpeptidase; PT: Prothrombin time; HEV: Hepatitis E virus; Ig: Immunoglobulin; RNA: Ribonucleic acid; DILI: Drug induced liver injury; CLD: Chronic liver disease; POD: Paracetamol overdose.