Chronic hepatitis B: Advances in treatment

doi:10.4254/wjh.v6.i5.284

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May 27, 2014 (publication date) through Dec 24, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. May 27, 2014; 6(5): 284-292
Published online May 27, 2014. doi: 10.4254/wjh.v6.i5.284

Table 3 Cross-resistance data for the most frequent resistant hepatitis B virus variants[43]

HBV variant	LVD	LdT	ETV	ADV	TDF
Wild-type	S	S	S	S	S
M204I/V	R	R	I	S	S
L180M + M204V	R	R	I	S	S
A181T/V	R	R	S	R	I
N236T	S	S	S	R	I
A181T/V + N236T	R	R	S	R	R
L180M + M204V/I ± I179T ± T184G ± S202I/G ± M250I/V	R	R	R	S	S

HBV: Hepatitis B virus; LVD: Lamivudine; LdT: Telbivudine; ETV: Entecavir; ADV: Adefovir; TDF: Tenofovir; S: Sensitive; I: Intermediate/reduced susceptibility; R: Resistant.

Citation: Santantonio TA, Fasano M. Chronic hepatitis B: Advances in treatment. World J Hepatol 2014; 6(5): 284-292
URL: https://www.wjgnet.com/1948-5182/full/v6/i5/284.htm
DOI: https://dx.doi.org/10.4254/wjh.v6.i5.284