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©2014 Baishideng Publishing Group Co.
World J Hepatol. Apr 27, 2014; 6(4): 230-242
Published online Apr 27, 2014. doi: 10.4254/wjh.v6.i4.230
Published online Apr 27, 2014. doi: 10.4254/wjh.v6.i4.230
Figure 1 Effect of melatonin and cisplatin on cell viability analyzed using an MTT assay.
Hepatocellular carcinoma (HepG2) cells were treated with various concentrations of melatonin and cisplatin for 24 h and 48 h. Both melatonin and cisplatin reduced the percent viability of HepG2 cells in a time and concentration-dependent manner (P < 0.001). The experiments were performed in triplicate, and the results are presented as the means ± SE.
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Citation: Bennukul K, Numkliang S, Leardkamolkarn V. Melatonin attenuates cisplatin-induced HepG2 cell death
via the regulation of mTOR and ERCC1 expressions. World J Hepatol 2014; 6(4): 230-242 - URL: https://www.wjgnet.com/1948-5182/full/v6/i4/230.htm
- DOI: https://dx.doi.org/10.4254/wjh.v6.i4.230