Disease dependent qualitative and quantitative differences in the inflammatory response to ascites occurring in cirrhotics

Table 1 Characteristics of the 57 subjects’ studies and of procalcitonin cytokines, and growth factors in plasma (mean ± SEM)

Parameter	ETOH	HCV	Malignancy	Cardiac
n	25	20	8	4
Male/female	18/7	14/6	5/3	2/2
CTP score	9.1 ± 0.2	8.2 ± 0.1	8.1 ± 0.1	8.1 ± 0.1
Laboratory tests
Creatinine (mg/dL)	1.2 ± 0.1	1.1 ± 0.1	1.2 ± 0.3	1.3 ± 0.2
Prothrombin time (s)	14.0 ± 0.4	13.8 ± 1.0	13.6 ± 0.2	12.5 ± 0.2
Total bilirubin (mg/dL)	1.4 ± 0.1	1.2 ± 0.2	1.4 ± 0.2	1.9 ± 0.3
Albumin (g/dL)	3.1 ± 0.2	3.2 ± 0.2	3.0 ± 0.4	3.2 ± 0.3
PCT	0.375 ± 0.215	0.440 ± 0.230	0.954 ± 0.242	0.092 ± 0.70
IL-1A	0.26 ± 0.146	0.160 ± 0.070	0.182 ± 0.106	0.135 ± 0.065
IL-1B	4.710 ± 2.252	1.747 ± 0.800	1.982 ± 0.106	1.610 ± 0.990
IL-2	2.498 ± 1.333	1.203 ± 0.548	2.690 ± 1.905	1.025 ± 0.375
IL-4	3.157 ± 1.429	2.580 ± 1.005	1.508 ± 0.422	1.430 ± 0.090
IL-6	83.791 ± 47.204	164.430 ± 70.891	105.392 ± 60.511	129.700 ± 112.500
IL-8	92.790 ± 44.935	334.513 ± 184.222	104.165 ± 61.670	16.415 ± 6.815
IL-10	1.335 ± 0.454	1.620 ± 0.779	1.117 ± 0.297	1.415 ± 0.615
MCP-1	111.139 ± 17.746	326.407 ± 137.768	116.052 ± 32.101	88.350 ± 35.150
IFNγ	1.148 ± 0.650	0.303 ± 0.058	0.712 ± 0.201	0.725 ± 0.525
TNF-α	3.887 ± 1.218	5.843 ± 2.248	4.805 ± 1.304	13.600 ± 11.80
EGF	37.451 ±11.642	92.453 ± 42.231	70.690 ± 36.431	126.00 ± 35.150
VEGF	11.658 ± 4.419	194.347 ± 130.788	20.523 ± 7.739	41.470 ± 32.870

No significant difference between any of these groups P > 0.05. HCV: Hepatitis C virus; PCT: Procalcitonin cytokines; IL: Interleukin; MCP-1: Monocyte chemotactic protein-1; IFN-γ: Interferon-γ; TNF-α: Tumor necrosis factor-α; EGF: Epidermal growth factor; VEGF: Vascular endothelial growth factor.