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©2014 Baishideng Publishing Group Co.
World J Hepatol. Feb 27, 2014; 6(2): 72-84
Published online Feb 27, 2014. doi: 10.4254/wjh.v6.i2.72
Published online Feb 27, 2014. doi: 10.4254/wjh.v6.i2.72
Control vs 60%-hepatectomy | Control vs 100%-OLT | Control vs 40%-SOLT | 60%-hepatectomy vs 100%-OLT | 60%-hepatectomy vs 40%-SOLT | 100%-OLT vs 40%-SOLT | |
Survival rate | P < 0.05 | NS | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 |
Liver damage score | P < 0.05 | P < 0.05 | P < 0.05 | NS | P < 0.05 | P < 0.05 |
TUNEL positive ratio | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 |
Caspase-3 positive ratio | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 |
AST | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 |
ALT | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 | NS |
T-Bil | NS | NS | P < 0.05 | NS | P < 0.05 | P < 0.05 |
PT-INR | P < 0.05 | p <0.05 | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 |
HA | P < 0.05 | p <0.05 | P < 0.05 | P < 0.05 | P < 0.05 | P < 0.05 |
Western blotting | ||||||
MDA | P < 0.05 | P < 0.05 | P < 0.05 | NS | P < 0.05 | NS |
4-HNE | P < 0.05 | P < 0.05 | P < 0.05 | NS | NS | NS |
ATM | P < 0.05 | P < 0.05 | P < 0.05 | NS | NS | NS |
γH2AX | P < 0.05 | P < 0.05 | P < 0.05 | NS | P < 0.05 | P < 0.05 |
PI3K | P < 0.05 | NS | P < 0.05 | P < 0.05 | NS | P < 0.05 |
Akt | P < 0.05 | NS | P < 0.05 | P < 0.05 | NS | P < 0.05 |
SOD | NS | NS | NS | NS | NS | NS |
Catalase | NS | NS | NS | NS | NS | NS |
MMP-9 | NS | NS | P < 0.05 | NS | P < 0.05 | P < 0.05 |
MMP-2 | NS | NS | P < 0.05 | NS | NS | NS |
TIMP-1 | P < 0.05 | NS | P < 0.05 | P < 0.05 | NS | P < 0.05 |
TIMP-2 | NS | NS | P < 0.05 | P < 0.05 | NS | P < 0.05 |
Zymography | ||||||
MMP-9 | P < 0.05 | P < 0.05 | P < 0.05 | NS | P < 0.05 | p <0.05 |
MMP-2 | NS | NS | NS | NS | NS | NS |
TIMP-1 | NS | NS | NS | NS | NS | NS |
TIMP-2 | NS | NS | NS | NS | NS | NS |
- Citation: Hori T, Uemoto S, Chen F, Gardner LB, Baine AMT, Hata T, Kogure T, Nguyen JH. Oxidative stress and extracellular matrices after hepatectomy and liver transplantation in rats. World J Hepatol 2014; 6(2): 72-84
- URL: https://www.wjgnet.com/1948-5182/full/v6/i2/72.htm
- DOI: https://dx.doi.org/10.4254/wjh.v6.i2.72