Evaluation of hepatocellular carcinoma development in patients with chronic hepatitis C by EOB-MRI

Table 2 Comparison of baseline characteristics between patients who have no hepatocellular carcinoma occurrence and hepatocellular carcinoma occurrence

Variables	No HCC occurrence n = 121	HCC occurrence n = 21	P value
Age (yr)	65.4 ± 12.9 (28-87)	70.3 ± 7.9 (51-79)	0.094
Sex (M/F)	59/62	11/10	0.759
AST (U/L)	46.0 ± 20.4 (11-110)	65.5 ± 31.6 (34-155)	0.000
ALT (U/L)	49.5 ± 32.5 (10-228)	64.4 ± 40.5 (31-205)	0.063
Serum albumin (g/dL)	4.1 ± 0.5 (2.4-5)	3.8 ± 0.5 (2.6-4.7)	0.030
Gamma-GT (IU/L)	67 ± 97 (14-811)	62 ± 43 (16-226)	0.829
ALP (U/L)	315 ± 158 (141-1206)	426 ± 212 (150-1006)	0.006
T.Chol (mg/dL)	178 ± 36 (90-280)	159 ± 35 (93-260)	0.029
T.Bil (mg/dL)	0.86 ± 0.42 (0.3-2.9)	0.86 ± 0.42 (0.3-2.9)	0.287
PT (%)	94 ± 15.5 (55.2-134)	86.8 ± 12.0 (67-110)	0.045
Platelet (× 103/μL)	142 ± 61 (42-338)	104 ± 40 (46-166)	0.006
AFP (ng/mL)	11.7 ± 26.3 (1.6-235)	30.3 ± 31.6 (4.2-116)	0.004
LI	1.53 ± 0.20 (1.11-2.15)	1.37 ± 0.10 (1.23-167)	0.000
Patients who received IFN, n (%)	37 (30.6)	2 (9.5)	0.062
Patients who achieved SVR, n (%)	25 (20.7)	2 (9.5)	0.366

HCC: Hepatocellular carcinoma; AST: Aspartate amino transferase; ALT: Alanine aminotransferase; Gamma-GT: Gamma-glutamyl transpeptidase; ALP: Alkaline phosphatase; T.Chol: Total cholesterol; T.Bil: Total bilirubin; PT: Prothrombin time; AFP: α-fetoprotein; LI: Liver-intervertebral disc ratio; IFN: Interferon; SVR: Sustained virologic response; F: Female; M: Male.