Palliative external-beam radiotherapy for bone metastases from hepatocellular carcinoma

Table 1 Incidence of bone metastases in clinical studies n (%)

Ref.	Study period	Patients	Extrahepatic Ms	Incidence of BMs	Rate of BMs in extrahepatic Ms
Kuhlman et al[13]	1979-1985	300		22 (7.3)
Liaw et al[14]	1983-1887	395		20 (5)
Katyal et al[15]	1992-1997	403	148 (36.7)	41(10.2)	28
Fukutomi et al[3]	1978-1987	269		12 (4.5)
	1988-1997	404		52 (12.9)
Natsuizaka et al[5]	1995-2001	482	65 (13.5)	25 (5.2)	38.50
Uchino et al[2]	1990-2006	2386	342 (14.3)	87 (3.6)	25.40
Senthilnathan et al[16]	2000-2008	209	51 (18)	5 (2)	10

BMs: Bone metastases; Ms: Metastases.