Ciclosporin does not attenuate intracranial hypertension in rats with acute hyperammonaemia

Table 1 Baseline values

Group	Weight (g)	MAP (mmHg)	ICP (mmHg)
PCA + ammonia infusion + Cs	295.5 ± 11.8	110 ± 4.2	1.0 ± 0.2
PCA + ammonia infusion + vehicle	326.2 ± 15.3	103 ± 4.0	0.8 ± 0.2
PCA + saline infusion + Cs	320.8 ± 12.4	116 ± 2.0	0.6 ± 0.2
PCA + saline infusion + vehicle	308.3 ± 14.7	106 ± 4.2	0.8 ± 0.3

PCA: Portacaval anastomosis; Cs: Ciclosporin; MAP: Mean arterial pressure; ICP: Increased intracranial pressure.