Noninvasive assessment of liver damage in chronic hepatitis B

Table 3 Between group comparisons and logistic regression results in chronic hepatitis B patients according to cirrhosis

Variable	Between group comparisons			Logistic regression analysis
	Non-cirrhotic (n = 76)	Cirrhotic (n = 13)	P value	Univariate OR (95%CI)	Multivariate OR (95%CI)
Gender (female/male)	33 (43.4)/43 (56.6)	6 (46.2)/7 (53.8)	0.999	1.1 (0.3-3.6)	-
Age (yr)	40.2 ± 12.3	49.08 ± 15.04	0.022	1.06 (1.01-1.1)	1.06 (1-1.11)
HGB	14.5 ± 2.03	14.6 ± 1.37	0.891	1.0 (0.7-1.39)	-
Platelet count (103μL)	190.5 (152-233.5)	152 (117-175)	0.051	0.9 (0.9-1)	-
INR	1.1 ± 0.1	1.1 ± 0.09	0.250	6.3 (0.09-478.1)	-
Albumine	4.04 ± 0.3	3.9 ± 0.4	0.210	0.2 (0.04-2.01)	-
Total bilirubin (mg/dL)	0.8 (0.6-1)	1 (0.6-1.3)	0.389	2.09 (0.5-8.7)	-
AST (IU/L)	41.5 (28-65)	66 (40-79)	0.078	1 (0.9-1.01)	-
ALT (IU/L)	54 (33-124)	69 (51-97)	0.419	1 (0.9-1.01)	-
AP (IU/L)	72 (61-89.5)	82 (62-116)	0.225	1.02 (1-1.03)	1.02 (1-1.04)
GGT (IU/L)	28 (20-50.5)	47 (26-50)	0.189	1.01 (1-1.02)	-
HBV DNA	269.5 (2-1000)	10.1 (0.4-1000)	0.339	1 (0.9-1.01)	-
HbeAg (negative/positive)	65 (85.5)/11 (14.5)	10 (76.9)/3 (23.1)	0.423	1.7 (0.4-7.4)	-
Neutrophil count	3.4 (2.8-4.7)	3.8 (3.04-4.1)	0.468	1.05 (0.7-1.5)	-
Lymphocyte count	2 (1.6-2.4)	2 (1.5-2.2)	0.493	0.6 (0.2-1.5)	-
N/L	1.8 (1.3-2.2)	2.04 (1.6-2.8)	0.160	1.3 (0.8-2.07)	-
APRI score	0.5 (0.3-1.08)	1.1 (0.7-1.7)	0.047	1.2 (0.8-2.05)	-

Values are expressed as n (%), mean ± SD or median(25^th-75^th percentiles). HGB: Hemoglobin; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; AP: Alkaline phosphatase; GGT: Gamma glutamyl transferase; HBV: Hepatitis B virus; HBeAg: Hepatitis B e antigen; N/L: Neutrophil-lymphocyte ratio; APRI: Aspartate aminotransferase/platelet ratio index.