Normal vitamin D levels are associated with spontaneous hepatitis B surface antigen seroclearance

Table 2 Results of multiple logistic regression analysis of spontaneous hepatitis B surface antigen seroclearance

Variables	OR (95%CI)	P value
Age > 35 (yr)	1.7 (1.25-2.8)	0.05
HBV DNA < 100 IU/mL	3 (2.6-4.2)	0.01
Serum 25 (OH) vitamin D > 20 ng/mL	2.6 (2.4-3.2)	0.02
HBeAg-negative	2.1 (1.2-3.1)	0.02
Duration of HBsAg-positivity > 8 years	1.6 (1.15-2.6)	0.04

Multiple logistic variables found to add a risk for spontaneous hepatitis B antigen clearance. HBV: Hepatitis B virus; HBsAg: Hepatitis B surface antigen; HBeAg: Hepatitis B e antigen; 25 (OH): 25-hydroxyvitamin.