Normal vitamin D levels are associated with spontaneous hepatitis B surface antigen seroclearance

Table 1 Laboratory, demographic and clinical data of the two groups n (%) or (mean ± SD)

Characteristic	Normal levels of 25 (OH) vitamin D (n = 44)	Below normal levels of 25 (OH) vitamin D (n = 9)	P value
Sex (male)	30 (68)	5 (55)	NS
Age (yr)	37 ± 12.3	33 ± 15.1	NS
BMI	25 ± 5.4	27 ± 3.2	NS
C-reactive protein (mg/L)	0.9 ± 2.57	0.7 ± 1.23	NS
Duration of HBsAg positivity (yr)	7.2 ± 3.4	8.4 ± 4.8	NS
HBeAg-positive	7 (16)	2 (22)	NS
Mean levels of 25 (OH) vitamin D (ng/mL)	31 ± 4	13.5 ± 7.2	< 0.001

Comparison of demographic and laboratory characteristics between patients with normal and below normal levels of serum vitamin D. Normal levels of 25-hydroxyvitamin [25 (OH)] vitamin D > 30 ng/mL. Below normal levels of 25 (OH) vitamin D ≤ 30 ng/mL. NS: Not significant; BMI: Body mass index; HBsAg: Hepatitis B surface antigen; HBeAg: Hepatitis B e antigen.