Differential expression of hepatic apurinic/apyrimidinic endonuclease 1, a DNA repair enzyme, in chronic hepatitis

Figure 3 Hepatic apurinic/apyrimidinic endonuclease 1 protein expression in patients with chronic liver disease. A, B: Western blot analysis showed that apurinic/apyrimidinic endonuclease 1 (APE-1) protein levels were reduced in HBV livers compared with normal and HCV livers; HCV livers showed no significant difference in APE-1 protein level compared with normal livers (^aP < 0.05 vs HCV, ^cP < 0.05 vs normal); C: Correlation between hepatocytic APE-1 protein determined by Western blot and immunohistochemistry in patients with chronic hepatitis. G3PDH: Anti-glyceraldehyde-3-phosphate dehydrogenase.