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World J Hepatol. Apr 27, 2013; 5(4): 160-169
Published online Apr 27, 2013. doi: 10.4254/wjh.v5.i4.160
Published online Apr 27, 2013. doi: 10.4254/wjh.v5.i4.160
n = 68 | Grade 0 | Grade 1 | Grade 2 | Grade 3 | OR (95%CI) | P value |
Diet | ||||||
HFD (n = 48) | 1 (2.10) | 19 (39.60) | 12 (25) | 16 (33.30) | NE | < 0.001 |
RD (n = 20) | 20 (100) | 0 (0) | 0 (0) | 0 (0) | BV | |
Melatonin | ||||||
10 mg/kg (n = 29) | 11 (37.90) | 9 (31) | 8 (27.60) | 1 (3.40) | 0.851 (0.72-0.99) | 0.04 |
5 mg/kg (n = 27) | 10 (37) | 10 (37) | 4 (14.90) | 3 (11.10) | ||
0 mg/kg (n = 12) | 0 (0) | 0 (0) | 0 (0) | 12 (100) | ||
Duration | ||||||
8 wk (n = 35) | 11 (31.40) | 10 (28.60) | 7 (20) | 7 (20) | 0.95 (0.34-2.66) | 0.92 |
4 wk (n = 33) | 10 (30.30) | 9 (27.30) | 5 (15.10) | 9 (27.30) | BV |
- Citation: Hatzis G, Ziakas P, Kavantzas N, Triantafyllou A, Sigalas P, Andreadou I, Ioannidis K, Chatzis S, Filis K, Papalampros A, Sigala F. Melatonin attenuates high fat diet-induced fatty liver disease in rats. World J Hepatol 2013; 5(4): 160-169
- URL: https://www.wjgnet.com/1948-5182/full/v5/i4/160.htm
- DOI: https://dx.doi.org/10.4254/wjh.v5.i4.160