Association between low molecular polypeptide 7 single nucleotide polymorphism and response to therapy in hepatitis C virus infection

Table 1 The demographic data of chronic hepatitis C virus patients infected with hepatitis C virus type 4a (sustained virological response vs non-response) after treatment

	NR (n = 48)	SVR (n = 56)	P value
Age (yr)			0.004
min-max	12-64	7-58
mean ± SD	44.17 ± 10.97	37.91 ± 10.91
Gender			0.9061
Female	9 (18.75)	10 (17.86)
Male	39 (81.25)	46 (82.14)
Weight (kg)	85.05 ± 13.98	78.54 ± 15.10	0.025
ALT	89.15 ± 62.70	48.39 ± 40.52	0.001
AFP	30.56 ± 22.58	11.28 ± 15.33	0.001
Viral load	686 150.38 ± 680 474.25	15 656.09 ± 452 782.09	0.001
Low fibrosis (F0-F1) (n = 39)	7 (17.95)	32 (82.05)	0.001
High fibrosis (F2-F4) (n = 65)	41 (63.08)	24 (36.92)	0.035
A0-A1 (n = 71)	24 (33.8)	47 (66.2)	0.006
A2-A3 (n = 33)	24 (72.73)	9 (27.27)	0.009

Data are expressed as mean ± SD or n (%). NR: Non-response; SVR: Sustained virological response; ALT: Alanine aminotransferase; AFP: Alpha-fetoprotein.

¹Not significant.