Homogeneous phenomenon of the graft when using different genotype characteristic of recipients/donors in living donor liver transplantation

Table 1 The proportional changes of G and A alleles of the CYP3A5*3 in the pyrosequencing with restriction fragment length polymorphism of peripheral blood mononuclear cells of the recipients and donors, and the liver graft biopsy samples after living donor liver transplantation

CYP3A5*3intron36986A > GA (wide type)Ssp I1	PS	Recipient	Donor	Graft(liver biopsy)		P value
						R vs G	D vs G
A > A/G, n = 10	A	86.23 ± 7.67	24.78 ± 3.90	n = 35	35.57 ± 7.52	< 0.0001	>0.05
	G	13.77 ± 7.67	75.23 ± 3.90		64.43 ± 7.52
A/G > A, n = 3	A	21.97 ± 1.32	73.13 ± 19.2	n = 5	68.92 ± 11.75	< 0.001	>0.05
	G	78.03 ± 1.32	26.87 ± 19.2		31.08 ± 11.75
A/G > G, n = 12	A	21.73 ± 5.81	6.44 ± 3.38	n = 33	9.95 ± 5.68	< 0.0001	>0.05
	G	78.27 ± 5.81	93.56 ± 3.38		90.05 ± 5.68
G > A, n = 2	A	3.06 ± 0.27	94.08 ± 5.87	n = 10	47.29 ± 9.44	< 0.0001	< 0.0001
	G	96.94 ± 0.27	5.92 ± 5.87		52.71 ± 9.44
G > A/G, n = 13	A	4.55 ± 1.88	22.97 ± 3.84	n = 31	18.75 ± 6.43	< 0.0001	= 0.033
	G	95.45 ± 1.88	77.03 ± 3.84		81.25 ± 6.43
A > G, n = 1	A	84.58	2.26	n = 5	11.60 ± 5.26	-	-
	G	15.42	97.74		88.39 ± 5.26
Total, n = 41				n = 119

¹Restriction enzyme for polymerase chain reaction-restriction fragment length polymorphism. D: Donor; G: Graft; PS: Pyrosequencing; R: Recipient.