Increased bone mineral density in patients with non-alcoholic steatohepatitis

Table 3 Serum hormone and cytokine results of the non-alcoholic steatohepatitis and the control group

Parameter	NASH groupmean ± SD (range)	Control group  mean ± SD (range)	P value
HOMA	5.7 ± 5.25 (1.1-23.59)	5.6 ± 10.1 (0.7-59.9)	0.192
Cortisol (μg/dL)	12.6 ± 5.8 (1.6-27)	11.6 ± 5.8 (2.9-28)	0.375
TSH (uIU/mL)	1.7 ± 1.09 (0.2-5.3)	1.36 ± 1 (0.01-4)	0.104
FT4 (ng/dL)	1.22 ± 0.19 (0.9-1.8)	1.22 ± 0.22 (0.8-107)	0.999
FSH (mIU/mL)	21 ± 41 (1.6-299)	19 ± 37 (0.3-177)	0.729
LH (mIU/mL)	10.4 ± 10.8 (1.2-44)	11 ± 15 (0.1-64)	0.974
E2 (pg/mL)	39.1 ± 72 (3.8-435)	41 ± 47 (2-199)	0.404
DHEAS (ug/dL)	190 ± 109 (25-501)	146 ± 90 (33-366)	0.071
iPTH (pg/mL)	46.3 ± 20 (18-130)	50 ± 16 (19-105)	0.086
25-OH-vit-D3 (ug/L)	17 ± 6 (5.1-39)	13 ± 7 (3.8-36)	< 0.0001
Testosterone (ng/mL)	2.5 ± 1.9 (0.03-5.8)	1.7 ± 1.9 (0.02-5.4)	0.075
IGF-1 (ng/mL)	141 ± 94 (30-527)	144 ± 47 (67-292)	0.099
TNF-α (pg/mL)	11.6 ± 6.7 (4-31.7)	14 ± 7 (2-4.9)	0.062
IL-6 (pg/mL)	2.2 ± 0.6 (2-4.9)	3 ± 2.4 (2-12)	0.8
IL-1 (pg/mL)	8.2 ± 16.5 (5-107)	5.3 ± 2 (5-17)	0.291
IGFBP-3 (ug/mL)	4.1 ± 1.68 (1.1-8.6)	4.2 ± 0.8 (2.6-6.02)	0.909

NASH: Non-alcoholic steatohepatitis; TNF-α: Tumor necrosis factor-α; IL-6: Interleukin-6; IGF-1: Insulin-like growth factor-1; IGFBP-3: Insulin-like growth factor binding protein-3; HOMA: Homeostasis model assessment; TSH: Thyroid stimulating hormone; LH: Luteinizing hormone; E2: Estradiol; DHEAS: Dehydroepiandrostenedione sulfate; iPTH: Intact parathormone; FT4: Free T4; FSH: Follicle-stimulating hormone.