Presence of disease specific autoantibodies against liver sinusoidal cells in primary biliary cirrhosis

Figure 2 Immunofluorescence of primary biliary cirrhosis, acute alcoholic hepatitis (AAH) or normal sections incubated with primary biliary cirrhosis, disease control or normal serum and fluorescein isothiocyanate -conjugated IgG secondary antibody. A-C: Primary biliary cirrhosis (PBC) section incubated with normal serum; D-F: Acute alcoholic hepatitis section incubated with normal serum; G-I: AAH section incubated with PBC serum; J-L: Normal section incubated with PBC serum, showing weak positive staining of cholangiocytes; M-O: PBC section incubated with steatohepatitis serum, showing positive staining of hepatocytes; P-R: Hepatitis B virus section incubated with steatohepatitis serum. Magnification × 200. FITC: Fluorescein isothiocyanate.