Relationship between vitamin D and IL-23, IL-17 and macrophage chemoattractant protein-1 as markers of fibrosis in hepatitis C virus Egyptians

Table 4 Laboratory data in the four subgroups of hepatitis C virus infected subjects

Item	Group Ia (bright hepatomegaly) (n = 14)	Group Ib (perihepatic fibrosis) (n = 11)	Group Ic (liver cirrhosis) (n = 11)	Group Id (HCC) (n = 14)	Normal (n = 25)	P value
IL-17 (ng/mL)	7.6	5.1	115.9	150.3	1.26	0.000
IL-23 (ng/mL)	76.8	51.2	259.3	225.9	6.7	0.000
Vit D (ng/mL)	19.8	19.4	10.9	9.7	39.1	0.000
Active vit D (ng/mL)	20.6	21	13	11.7	41.1	0.000
Viral load (IU/mL)	66.3	42.4	165.1	231.1	0	0.000
MCP-1 (ng/mL)	910.3	838.8	2090.9	2448	237.34	0.000

Vit: Vitamin; IL: Interleukin; MCP-1: Macrophage chemoattractant protein-1; HCC: Hepatocellular carcinoma.