Life style modification improves insulin resistance and liver histology in patients with non-alcoholic fatty liver disease

Table 5 Anthropometric, biochemical and histological characteristics of patients with paired liver biopsy (n = 8)

Variable	Pre-intervention	Post-intervention	P value1
BMI (kg/m2)	27.6 ± 3.8	26.0 ± 2.4	0.012
WC (cm)	96.3 ± 7.6	91.0 ± 6.3	0.01
ALT (U/L)	99.8 ± 37.2	34.0 ± 16.8	0.01
HOMA-IR	6.1 ± 3.8	1.04 ± 0.5	0.01
NASH score	5.3 ± 1.5	3.3 ± 1.5	0.02

¹Wilcoxon sign rank test. BMI: Body mass index; WC: Waist circumference; ALT: Alanine aminotransferase; HOMA-IR: Homeostasis model assessment-estimated insulin resistance; NASH: Nonalcoholic steatohepatitis.