Life style modification improves insulin resistance and liver histology in patients with non-alcoholic fatty liver disease

Table 4 Sub-group analysis of the compliant group - exercise alone and both exercise and diet modification and comparison with non-compliant group

Variable	Non-compliant (n = 15)			Exercise (n = 12)			Exercise and diet (n = 33)
	Pre	Post	P value1	Pre	Post	P value1	Pre	Post	P value1
BMI (kg/m2)	27.6 ± 3.8	27.7 ± 3.5	NS	23.0 ± 1.4	21.7 ± 1.6	NS	28.5 ± 2.4	26.6 ± 2.7	< 0.001
WC (cm)	99.2 ± 7.00	98.7 ± 8.4	NS	88.0 ± 7.0	85.4 ± 7.2	0.001	99.5 ± 7.2	93.6 ± 5.5	< 0.001
WHR	0.9 ± 0.3	0.9 ± 0.1	NS	0.9 ± 0.3	0.9 ± 0.1	0.006	0.9 ± 0.6	0.9 ± 0.1	0.001
ALT (U/L)	82.0 ± 45.0	78.2 ± 18.6	NS	69.8 ± 32.3	34.6 ± 13.1	0.001	90.3 ± 46.1	43.8 ± 19.4	0.001
HOMA-IR	8.7 ± 4.1	10.5 ± 9.8	NS	6.2 ± 4.6	1.2 ± 0.8	0.002	6.5 ± 4.4	1.4 ± 1.1	< 0.001

¹Wilcoxon signed rank test. BMI: Body mass index; WC: Waist circumference; WHR: Waist-hip ratio; ALT: Alanine aminotransferase; HOMA-IR: Homeostasis model assessment-estimated insulin resistance. NS: Not significant.