Prevalence of HIV and HCV infections in two populations of Malian women and serological assays performances

Table 3 Predictive values of the Monolisa test ratio in both series of samples

MONOLISA HCV-Ab Ag	Series	N+	LIA-HCV			PPV, %	PCR-RNA-HCV			PPV, %
Test ratio			Neg	Pos	Ind		Neg	Pos	Ind
(1-3)	1	10	6	0	4	0	6	0	41	0
(> 3)	1	7	1	1	5	50	6	1	0	14.3
(1-3)	2	7	2	1	4	33.3	7	0	0	0
(> 3)	2	14	0	14	0	100	1	13	0	92.9
(1-3)	1 + 2	17	8	1	8	11.1	13	0	41	0
(> 3)	1 + 2	21	1	15	5	93.8	7	14	0	66.7

¹Four samples [whose test ratio = (1-3)] were not tested with polymerase chain reaction (PCR) because Monolisa results were not reproducible and the Innotest was negative in each case. Ind: Indeterminate result; PPV: Positive predictive value of hepatitis C virus (HCV) Monolisa test for antibody or RNA detection; Series 1: Young women; Series 2: Women over 50 years old; Series (1 + 2): Overall cohort (young and older women); N+: Numbers of positive results with Monolisa HCV according to the test ratio value.