Noninvasive predictors for liver fibrosis in patients with nonalcoholic steatohepatitis

Table 3 Predictors of liver fibrosis and histological stage in nonalcoholic steatohepatitis cases (n = 70)

	Absent	Fibrosis (%)		Bridging	Cirrhosis (%)
		Perisinusoidal/pericellular	Periportal
Gender
Male	50.0	22.2	16.6	8.3	2.7
Female	38.2	47.0	5.9	8.9	-
Age (yr)
> 45	45.8	39.7	6.25	6.25	2.1
< 45	41.0	22.7	22.7	13.6	-
Body mass index (kg/m2)					-
18.5-24.9	33.3	0	33.3	33.3
25.0-29.9	44.4	41.6	8.3	5.5	-
30.0-39.9	50.0	21.4	14.2	10.7	3.5
> 40	25.0	75.0	0	0	-
Central obesity
Present	38.0	36.0	16.0	8.0	2.0
Absent	60.0	30.0	0	10.0	-
AST/ALT > 1	20.0	20.0	20.0	40.0	-
AST/ALT < 1	53.1	29.6	10.9	4.6	1.5
GGT/ALT > 1	52.1	26.0	13.0	8.63	-
GGT/ALT < 1	54.3	30.4	8.6	6.5	2.1
Platelet count
Low	66.6	33.4	0	0	0
Normal	44.0	35.0	10.5	9.0	1.5
Ferritin
Elevated	33.4	0	66.6	0	0
Normal	44.0	36.5	9.0	9.0	1.5
Fasting insulin
Elevated	28.5	14.5	28.5	28.5	-
Normal	43.6	37.1	9.7	8.0	1.6
Fasting c-peptid
Elevated	59.0	27.2	6.8	6.8	-
Normal	44.0	32.0	16.0	8.0	2.3
Hypertension
Present	28.5	52.3	9.5	9.5	-
Absent	53.0	26.5	12.2	6.1	2.0
Diabetes
Present	19.0	47.6	14.2	14.2	4.7
Absent	55.1	28.5	10.2	6.1	-
Hypertriglyceridemia
Present	38.8	33.4	16.6	8.3	-
Absent	47.0	38.2	5.8	5.8	3.0
Insulin resistance
Present	37.0	40.7	18.5	3.7	3.7
Absent	77.2	13.6	-	9.2	-

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; GGT: γ-glutamyltransferase.