Noninvasive predictors for liver fibrosis in patients with nonalcoholic steatohepatitis

Table 2 Predictors of liver fibrosis and liver histology (steatosis and necroinflammation) in patients with nonalcoholic steatohepatitis

	Steatosis (n = 70)			Necroinflammation (Grade) (n = 70)
	Mild (%)	Moderate (%)	Severe (%)	Mild (%)	Moderate (%)	Severe (%)
Gender
Male	38.9	38.9	22.1	36.1	55.5	8.3
Female	41.2	35.3	23.5	20.6	64.7	14.7
Age (yr)
> 45	35.4	37.5	27.0	25.0	62.5	12.5
< 45	45.4	36.3	18.1	36.3	59.0	4.5
Body mass index (kg/m2)
18.5-24.9	0	66.6	34.4	33.3	33.4	33.3
25.0-29.9	34.2	42.9	22.9	31.4	60.0	8.6
30.0-39.9	50.0	21.5	28.5	32.1	53.6	14.3
> 40	25.0	75.0	0	50.0	50.0	0
Central obesity
+	40.0	38.0	22.0	28.5	61.2	10.2
-	35.0	35.0	30.0	28.5	57.1	14.2
AST/ALT > 1	40.0	20.0	40.0	20.0	40.0	40.0
AST/ALT < 1	37.5	39.0	23.4	29.6	60.9	9.3
GGT/ALT > 1	36.3	27.2	36.3	31.8	50.0	18.1
GGT/ALT < 1	38.2	42.5	19.1	25.5	65.9	8.6
Platelet count
Low	33.4	0	66.6	33.4	33.3	33.4
Normal	39.3	37.8	22.7	36.3	53.0	10.6
Ferritin
Elevated	0	33.4	66.6	0	33.4	66.6
Normal	39.3	37.8	22.7	28.7	62.1	10.6
Fasting insulin
Elevated	14.4	28.5	57.1	14.4	71.4	14.4
Normal	42.0	35.5	22.5	30.6	62.0	11.2
Fasting c-peptid
Elevated	31.2	37.5	31.2	15.6	71.8	12.5
Normal	45.9	35.1	18.9	37.8	51.3	10.8
Hypertension
Present	38.1	33.4	28.5	19.0	62.0	19.0
Absent	38.7	38.7	22.4	32.6	59.2	8.2
Diabetes
Present	38.1	33.4	28.5	23.8	57.1	14.2
Absent	36.7	38.7	24.4	28.5	61.2	10.2
Hypertriglyceridemia
Present	36.2	38.8	25.0	19.4	66.6	13.8
Absent	41.0	35.2	23.5	38.2	52.9	8.8
Insulin resistance
Present	37.9	34.4	27.5	24.1	65.5	10.3
Absent	40.0	40.0	20.0	50.0	40.0	10.0

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; GGT: γ-glutamyltransferase.