MELD score, insulin-like growth factor 1 and cytokines on bone density in end-stage liver disease

doi:10.4254/wjh.v3.i6.157

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 3, Issue 6

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (3400)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-1) series, Tables (1-5) series.

Item

Count

PDF

290

HTML

2435

Figures (1-1)

498

Tables (1-5)

177

Sum=3400

Jun 27, 2011 (publication date) through Jul 26, 2024

Times Cited of This Article

Times Cited (10)

Journal Information of This Article

Publication Name

World Journal of Hepatology

ISSN

1948-5182

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Brief Article

World J Hepatol. Jun 27, 2011; 3(6): 157-163
Published online Jun 27, 2011. doi: 10.4254/wjh.v3.i6.157

Table 2 Clinical and Biochemical Data by Etiology of Cirrhosis

Variable	Viral	Alcohol	Cholestasis	Other
Variable	n = 46	n = 20	n = 25	n = 26
BMI (kg/m²)	25.4 (5.1)	24.4 (5.3)	23.3 (3.2)	25.8 (5.9)
MELD score	15.1 (6.14)	16.2 (6.14)	14.2 (5.06)	15.6 (6.51)
Corrected calcium (nmol/L)	2.39 (0.28)	2.44 (0.21)	2.37 (0.11)	2.41 (0.22)
PTH (ng/L)	2.14 (1.2)^a	3.73 (2.7)	2.83 (1.5)	3.48 (3.9)
25OHD (μg/L)	30.6 (16.1)	34.4 (20.1)	37.0 (20.2)	28.7 (17.0)
Testosterone (nmol/L)	12.7 (11.2)	7.0 (4.5)^b	15.7 (7.4)	12.2 (11.5)
IGF-1 (μg/L)	34.5 (47.3)	28.3 (27.1)	45.9 (47.7)	59.5 (79.2)
TNFα (ng/L)	16.1 (10.9)	13.7 (6.7)	15.0 (8.4)	13.0 (5.0)
IL-6 (ng/L)	26.7 (72.4)	19.3 (20.7)	7.1 (5.3)	9.9 (12.2)
UNTx (nmol BCE/mmol creatinine)	54.9 (38.0)	69.3 (25.2)	56.5 (41.6)	53.7 (36.2)

^aPTH significantly lower in viral group than in alcohol and other (P < 0.05);

^bTestosterone significantly lower in alcohol group than in cholestasis (P < 0.05). BCE: bone collagen equivalents; PTH: Parathyroid hormone; BMI: Body mass index; 25OHD: 25-hydroxyvitamin D; IGF-1: Insulin-like growth factor-1; TNFα: Tumor necrosis factor-α; IL-6: Interleukin-6. Values are presented as mean (SD)

Citation: Mitchell R, McDermid J, Ma MM, Chik CL. MELD score, insulin-like growth factor 1 and cytokines on bone density in end-stage liver disease. World J Hepatol 2011; 3(6): 157-163
URL: https://www.wjgnet.com/1948-5182/full/v3/i6/157.htm
DOI: https://dx.doi.org/10.4254/wjh.v3.i6.157