MELD score, insulin-like growth factor 1 and cytokines on bone density in end-stage liver disease

Table 1 Patient demographics and biochemical data

Variable	n = 117
Age in years	50.4 (10.5)
Male gender - no. (%)	74 (63%)
Etiology of liver disease - no. (%)
Viral	46 (39%)
Alcohol	20 (17%)
Cholestasis	25 (21%)
Other	26 (22%)
BMI (kg/m2)	24.8 (5.0)
Current smoking - no. (%)	43 (37%)
History of fracture - no. (%)	10 (9%)
MELD score	15.2 (6.0)
Calciuma (N 2.1 - 2.6 ng/L)	2.41 (0.22)
PTH - mean (SD)(N 1.1 - 6.8 ng/L)	2.86 (2.44)
25 OHD (N 40 - 200 μg/mL)	32.2 (19.5)
Total testosterone (N 10 - 29.5 nmol/L)	12.0 (9.9)
IGF-1 (μg /mL) (N, age and sex dependent)	41.3 (54.0)
TNFα (N < 8.1 ng /mL)	14.8 (8.7)
IL-6 (N < 9.7 ng /mL)	17.1 (46.2)
UNTx (N < 81 nmol BCE/ mmol creatinine)	57.3 (36.4)

aCorrected calcium presented; Values are presented as mean (SD) unless indicated otherwise, N: normal range. BCE: bone collagen equivalents; PTH: Parathyroid hormone; BMI: Body mass index; 25OHD: 25-hydroxyvitamin D; IGF-1: Insulin-like growth factor-1; TNFα: Tumor necrosis factor-α; IL-6: Interleukin-6