HBV vaccine efficacy and detection and genotyping of vaccineé asymptomatic breakthrough HBV infection in Egypt

Table 2 Frequency of HBs antigen by ELISA and AxSYM among r-HBsAg vaccine responders and non responders

	Anti-HBs IgG antibody level	Samples tested	HBs Ag
			(ELISA)	(AxSYM)
		n	Positive n (%)	Positive n ( %)
Group I Children (2-<4 years)	Low	27	0	2 (7.4)
	Negative	8	0	3 (37.5)
	High	20	0	0
Group II Children (4-13 years)	Low	178	4 (2.25)	17 (9.55)
	Negative	53	1 (1.88)	11 (20.8)
	High	14	0	1a (7.14)
Group III Adults (20-47 years)	Low	32	2 (6.25)	2 (6.25)
	Negative	21	2 (9.52)	5 (23.8)
	High	7	0	0
Total		360	9 (2.5)	41b (11.39)

^aExamination of 41 high anti-HBs IgG antibodies serum samples demonstrated that all markers tested were negative, except for one sample that was positive for HBsAg by AxSYM;

^bThe number of positive samples for HBs antigen were 41 samples by AxSYM in comparison with 9 samples.