Asymptomatic primary biliary cirrhosis is not associated with increased frequency of cardiovascular disease

Table 4 Characteristics of cases with and without fatigue

	With fatigue	Without fatigue	P value
	n = 74	n = 104
Age (years)	54.3 (22-73)	57.1 (31-74)	0.4
Female gender	71 (95.9)	92 (88.5)	0.08
Caucasian	63 (85.1)	93 (89.4)	0.4
AMA	57 (77)	79 (78.2)	0.9
BMI (kg/m2)	27 (17.6-39.2)	26.2 (17.6-51)	0.4
Hypertension	18 (24.3)	29 (28.2)	0.6
Diabetes	10 (13.5)	15 (14.6)	0.8
Smoking	26 (35.1)	36 (35.6)	0.9
Stage of fibrosisa			0.7
0-2	26 (37.1)	38 (40.4)
3-4	44 (62.9)	56 (59.6)
Total cholesterol (mg/dL)	203 (83-612)	217 (81-2055)	0.06
LDL (mg/dL)	123.5 (29-539)	131 (12-505)	0.2
HDL (mg/dL)	55 (20-118)	54 (17-163)	0.5
Triglyceride (mg/dL)	110 (32-462)	104 (32-736)	0.6
Statin use	6 (8.1)	9 (8.7)	0.9
CAD	7 (9.5)	7 (6.7)	0.5
TIA	1 (1.4)	0 (0)	0.4
Stroke	2 (2.7)	0 (0)	0.2
Any CVD	10 (13.5)	7 (6.7)	0.1

AMA: antimitochondrial antibody; BMI: body mass index; LDL: low density lipoprotein; HDL: high density lipoprotein; CAD: coronary artery disease; TIA: transient ischemic attack; CVD: cardiovascular disease. Continuous variables are expressed as median (range). Categorical variables are expressed as number (frequency).

^aBased on the Metavir scoring system