Guidelines For Clinical Practice
Copyright ©2010 Baishideng.
World J Hepatol. Mar 27, 2010; 2(3): 103-113
Published online Mar 27, 2010. doi: 10.4254/wjh.v2.i3.103
Table 3 Summary of the results obtained so far with Bevacizumab and Bevacizumab-based combinations in HCC
DevelopmentComments
BevacizumabAs single agent, i.v. routeActive (high DCR), but increased risk of bleeding from esophageal varices
As single agent, i.a. routePromising early results
In combination with other molecularly targeted agents, e.g. erlotininibActive (high ORR), but toxic
In combination with chemotherapyNot particularly active and toxic