Minimizing liver uptake of cationic 99mTc radiotracers with ether and crown ether functional groups

Figure 9 Planar images of the SD rats administered with ~1. 0 mCi of ^99mTcN-MPO in the absence and presence of cyclosporin-A at 30 and 60 min post-injection. Pre-treatment with cyclosporin-A (14 mg/kg) results in more liver radioactivity accumulation and slower liver clearance.