Differential expression of cell cycle regulators in HCV-infection and related hepatocellular carcinoma

Table 3 Immunohistochemical reactivity for cyclin E in patients with well-differentiated and poorly-differentiated (HCC) (mean ± SE) n(%)

Groups	Positive expression	Immunohistochemical reactivity			Stained cells
		Mild < 5%	Moderate 5%-49%	Marked 50%-100%
Well-differentiated HCC (n = 15)	6 (40.0)	2 (33.3)	4 (66.7)	0 (0)	25.3 ± 5.9
Poorly-differentiated HCC (n = 15)	6 (40.0)	0 (0)	0 (0)	6 (100)	82.5 ± 2.1a

^aP < 0.01 vs well differentiated HCC.