Correlation between the interleukin-36 subfamily and gut microbiota in patients with liver cirrhosis: Implications for gut-liver axis imbalance

Table 1 General clinical characteristics of the study population

Variables	HC (n = 29)	LC (n = 61)	χ²/t	P value
Sex (male)	23.00 (79.30%)	50.00 (82.00%)	0.248	0.763
Age (years)	51.65 ± 8.34	53.89 ± 9.38	-1.091	0.278
WBC (109/L)	5.58 ± 1.21	4.60 ± 2.48	2.024	0.046
HB (g/L)	146.22 ± 35.68	110.82 ± 29.99	4.918	< 0.001
PLT (109/L)	230.10 ± 54.88	109.62 ± 73.07	7.877	< 0.001
Alb (g/L)	47.09 ± 4.74	32.87 ± 6.92	9.990	< 0.001
ALT (U/L)	20.59 ± 6.92	43.64 ± 6.92	-1.803	0.075
AST (U/L)	23.00 ± 9.39	58.62 ± 60.48	-3.145	0.002
ALP (U/L)	70.28 ± 15.33	117.16 ± 52.84	-4.673	< 0.001
γ-GGT (U/L)	23.17 ± 12.72	123.61 ± 333.17	-1.618	0.109
TBIL (umol/L)	10.81 ± 3.52	65.82 ± 93.82	-3.147	0.002
Cr (umol/L)	71.25 ± 8.79	71.93 ± 28.85	-0.149	0.882

LC: Liver cirrhosis; HC: Healthy controls; HB: Hemoglobin; PLT: Blood platelet; Alb: Albumin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; γ-GGT: Gamma-glutamyltransferase; TBIL: Total bilirubin; Cr: Creatinine; WBC: White blood cell.