Progress of research on glucose transporter proteins in hepatocellular carcinoma

Table 1 Currently common experimental drugs targeting glucose transporter proteins

Ref.	Name	Target GLUTs	Ways to interfere with GLUT action
Ebstensen and Plagemann[86]	Cytochalasin B	Competition with GLUTs for binding sites	Reduces glucose supply to cancer cells
Ceballos et al[88]	Glupin	GLUT1, and GLUT3	Inhibition of glucose uptake
Karageorgis et al[89]	Chromopynones	GLUT1, and GLUT3	Inhibition of glucose uptake
Reckzeh et al[90]	Glutor	GLUT1, 2, and 3	Inhibits glycolytic processes
Guo et al[91]	Rapaglutin A	GLUT1, 3, and 4	Stimulates insulin secretion and inhibits GLUT uptake
Wood et al[93]	Fasentin	GLUT1	Inhibits glycolytic processes
Siebeneicher et al[94]	WZB117, BAY-876	GLUT1	Enhancing the sensitivity of HCC cells to chemotherapeutic agents

GLUT: Glucose transporter proteins; HCC: Hepatocellular carcinoma.