Mogroside V protects against acetaminophen-induced liver injury by reducing reactive oxygen species and c-jun-N-terminal kinase activation in mice

Figure 4 Mogroside V inhibits acetaminophen-induced c-jun-N-terminal kinase activation in the liver of acetaminophen-treated mice. Mice were pretreated with or without Mogroside V for one hour prior to acetaminophen administration, and the protein level of phosphorylated c-jun-N-terminal kinase (JNK) and total JNK were measured six hours later. n = 3-5 per group. ^aP < 0.05, ^bP < 0.01. MV: Mogroside V; APAP: Acetaminophen; GSH: Glutathione.