Effect of portal pressure gradient reduction on outcomes after transjugular intrahepatic portosystemic shunt in portal hypertension patients

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Mar 27, 2025 (publication date) through Apr 1, 2025

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Mar 27, 2025; 17(3): 103261
Published online Mar 27, 2025. doi: 10.4254/wjh.v17.i3.103261

Table 2 Univariate and multivariate Cox regression analyses for shunt dysfunction before and after propensity score matching

Characteristics	Before PSM, univariate analyses (n = 815)			Before PSM, multivariate analyses (n = 815)			After PSM, univariate analyses (n = 662)			After PSM, univariate analyses (n = 662)
Characteristics	HR	95%CI	P	HR	95%CI	P	HR	95%CI	P	HR	95%CI	P
Group B	0.372	0.233-0.594	< 0.001^b	0.452	0.261-0.783	0.005^b	0.482	0.297-0.783	0.003^b	0.496	0.305-0.807	0.005^b
Alkaline phosphatase	0.538	0.349-0.830	0.005^b	0.545	0.350-0.849	0.007^b	0.615	0.394-0.958	0.031^a	0.64	0.411-0.998	0.049^a
Kalium	0.338	0.117-0.974	0.045^a	0.302	0.099-0.922	0.035^a
Portal vein diameter	4.075	1.885-8.808	< 0.001^b	1.663	0.656-4.214	0.284
C-Reactive protein	0.926	0.854-1.004	0.062
Serum urea nitrogen	0.69	0.422-1.128	0.139
Right hepatic vein free pressure	1.535	0.846-2.786	0.159
Natrium	0.699	0.412-1.187	0.185
Age	1.549	0.671-3.577	0.305

^aP < 0.05.

^bP < 0.01.

HR: hazard ratio; PSM: Propensity score matching.

Citation: Wang ZB, Zhu B, Meng MM, Wu YF, Zhang Y, Li DZ, Tian H, Wang FC, Lv YF, Ye QX, Liu FQ. Effect of portal pressure gradient reduction on outcomes after transjugular intrahepatic portosystemic shunt in portal hypertension patients. World J Hepatol 2025; 17(3): 103261
URL: https://www.wjgnet.com/1948-5182/full/v17/i3/103261.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i3.103261